产品货号:
Z22073
中文名称:
NKIRAS1抗体
英文名称:
Anti-NKIRAS1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-NKIRAS1 Antibody |
指标别名 | KBRAS1;kappaB-Ras1;KBRAS1;NF-kappa-B inhibitor-interacting Ras-like protein 1;I-kappa-B-interacting Ras-like protein 1;Kappa B-Ras protein 1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC |
基因名称 | NKIRAS1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | KappaB ras antibody was raised against a 18 amino acid synthetic peptide from near the center of human KappaB ras 1.The immunogen is located within amino acids 80 - 130 of KappaB ras. |
计算分子量 | 22kDa |
成分 | KappaB ras Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | KappaB ras Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | KappaB ras-1 (百B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with I百B (I百B),an inhibitor of the transcription factor NF-百B.I百B exists in two homologous forms,I百B-alpha and I百B-beta,although I百B-beta contains a unique 47-amino acid region within its ankyrin domain.While inactive I百B-alpha-NF-百B complexes can shuttle in and out of the nucleus,I百B-beta-NF-百B complexes are retained exclusively in the cytoplasm.It is suggested that kappaB-ras proteins preferentially bind to the I百B-beta form through this unique insert within the ankyrin region,thus modulating the cellular location of I百B-beta and regulating the rate of degradation of I百B-beta.This antibody detects both kappaB-ras1 and kappaB-ras2. |
Uniprot ID | Q9NYS0 |
基因名全称 | NFKB inhibitor interacting Ras-like 1 |
蛋白名全称 | NFKB inhibitor interacting Ras-like 1 |
推荐稀释比 | KappaB ras antibody can be used for detection of KappaB ras by Western blot at 2μg/mL.Antibody can also be used for immunohistochemistry starting at 1μg/mL.Antibody validated:Western Blot in mouse samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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